Myocardial infarction; MI; Acute MI; ST-elevation myocardial infarction; Non-ST-elevation myocardial infarction; NSTEMI; CAD - heart attack; Coronary artery disease - heart attack
Most heart attacks are caused by a blood clot that blocks one of the coronary arteries. The coronary arteries bring blood and oxygen to the heart. If the blood flow is blocked, the heart is starved of oxygen and heart cells die.
The medical term for this is myocardial infarction.
You feel a tight band of pain around your chest. The pain moves from your chest to your arms, shoulder, and neck. What could your pain mean? Could it be a heart attack, could it be the big one? Heart attacks are caused by interruption of blood supply to part of the heart. If the blood flow is blocked, your heart is starved of oxygen and heart cells die. A hard substance called plaque can build up in the walls of your coronary arteries. This plaque is made up of cholesterol and other cells. A heart attack can occur as a result of plaque buildup or the rupture of one of these plaques. We're not sure why heart attacks occur when they do. You may have a heart attack when you are resting or asleep, or after a sudden increase in physical activity, when you are outside in cold weather, or after a sudden, severe emotional or physical stress, including an illness. So, how is a heart attack treated? If you go to the hospital for a suspected heart attack, a doctor or nurse will listen to your chest with a stethoscope. You will have a blood test to look for heart damage. A coronary angiography test can show your doctor how well blood is moving through your heart. If blood moves slowly, or not at all through your coronary arteries, you have either a narrowed, or blocked artery. Other tests can look at the valves and chambers of your heart and check for abnormal heart rhythms. If you've had a heart attack, doctors can do an emergency procedure called angioplasty. This surgery or procedure can open narrowed or blocked blood vessels. Usually they'll place a small, metal mesh tube, called a stent, in your artery to help keep it open. You may also receive drugs to break up the clot in your artery. Sometimes, doctors will do heart bypass surgery to get blood flowing to your heart muscle again. After you are treated in the hospital for a heart attack, you may need to take medicines to thin your blood, to protect your heart, or to improve your cholesterol levels. You may need to take these medicines for the rest of your life. Most people who have had a heart attack also need cardiac rehabilitation. This will help you slowly increase your exercise level and learn how to follow a healthy lifestyle. After you have a heart attack, your chance of another is higher. How well you do after a heart attack depends on the damage to your heart and where the damage is, and what steps you take to prevent another one. If your heart can no longer pump blood to your body as well as it used to, you may have heart failure and will need lifelong treatment. Usually a person who has had a heart attack can slowly go back to normal activities, but you will need to take steps to prevent another heart attack.
The interior of the heart is composed of valves, chambers, and associated vessels.
The external structures of the heart include the ventricles, atria, arteries and veins. Arteries carry blood away from the heart while veins carry blood into the heart. The vessels colored blue indicate the transport of blood with relatively low content of oxygen and high content of carbon dioxide. The vessels colored red indicate the transport of blood with relatively high content of oxygen and low content of carbon dioxide.
Plaque may build-up in a coronary artery at the site of a tear in the lining of the vessel.
A heart attack or acute myocardial infarction (MI) occurs when one of the arteries that supplies the heart muscle becomes blocked. Blockage may be caused by spasm of the artery or by atherosclerosis with acute clot formation. The blockage results in damaged tissue and a permanent loss of contraction of this portion of the heart muscle.
Various phases can be seen through ECG wave tracings following a heart attack. Hyperacute phase begins immediately after a heart attack. Fully evolved phase starts a few hours to days after a heart attack. Resolution phase appears a few weeks after a heart attack. Stabilized chronic phase is the last phase and typically has permanent pathological changes compared to a normal ECG tracing.
The coronary arteries supply blood to the heart muscle. The right coronary artery supplies both the left and the right heart; the left coronary artery supplies the left heart.
The coronary arteries supply blood to the heart muscle. The right coronary artery supplies both the left and the right heart; the left coronary artery supplies the left heart.
Symptoms of a possible heart attack include chest pain and pain that radiates down the shoulder and arm. Some people (older adults, people with diabetes, and women) may have little or no chest pain. Or, they may experience unusual symptoms (shortness of breath, fatigue, weakness). Women are more likely than men to have symptoms of nausea, vomiting, back or jaw pain, and shortness of breath with chest pain.
Pain from a heart attack may sometimes radiate to the jaw and teeth. Chest pain is a major symptom of heart attack, but other symptoms such as weakness, shortness of breath, nausea, or vomiting may also occur.
Causes
A substance called plaque can build up in the walls of your coronary arteries. This plaque is made up of cholesterol and other cells.
A heart attack may occur when:
- A disruption in the plaque occurs. This triggers blood platelets and other substances to form a blood clot at the site that blocks most or all of the oxygen-carrying blood from flowing to a part of the heart muscle. This is the most common cause of heart attack.
The cause of heart attack is not always known, but there are well known risk factors.
Heart attack may occur:
- When you are resting or asleep
- After a sudden increase in physical activity
- When you are active outside in cold weather
- After sudden, severe emotional or physical stress, including an illness
Many risk factors may lead to the development of plaque buildup and a heart attack.
You feel a tight band of pain around your chest. The pain moves from your chest to your arms, shoulder, and neck. What could your pain mean? Could it be a heart attack, could it be the big one? Heart attacks are caused by interruption of blood supply to part of the heart. If the blood flow is blocked, your heart is starved of oxygen and heart cells die. A hard substance called plaque can build up in the walls of your coronary arteries. This plaque is made up of cholesterol and other cells. A heart attack can occur as a result of plaque buildup or the rupture of one of these plaques. We're not sure why heart attacks occur when they do. You may have a heart attack when you are resting or asleep, or after a sudden increase in physical activity, when you are outside in cold weather, or after a sudden, severe emotional or physical stress, including an illness. So, how is a heart attack treated? If you go to the hospital for a suspected heart attack, a doctor or nurse will listen to your chest with a stethoscope. You will have a blood test to look for heart damage. A coronary angiography test can show your doctor how well blood is moving through your heart. If blood moves slowly, or not at all through your coronary arteries, you have either a narrowed, or blocked artery. Other tests can look at the valves and chambers of your heart and check for abnormal heart rhythms. If you've had a heart attack, doctors can do an emergency procedure called angioplasty. This surgery or procedure can open narrowed or blocked blood vessels. Usually they'll place a small, metal mesh tube, called a stent, in your artery to help keep it open. You may also receive drugs to break up the clot in your artery. Sometimes, doctors will do heart bypass surgery to get blood flowing to your heart muscle again. After you are treated in the hospital for a heart attack, you may need to take medicines to thin your blood, to protect your heart, or to improve your cholesterol levels. You may need to take these medicines for the rest of your life. Most people who have had a heart attack also need cardiac rehabilitation. This will help you slowly increase your exercise level and learn how to follow a healthy lifestyle. After you have a heart attack, your chance of another is higher. How well you do after a heart attack depends on the damage to your heart and where the damage is, and what steps you take to prevent another one. If your heart can no longer pump blood to your body as well as it used to, you may have heart failure and will need lifelong treatment. Usually a person who has had a heart attack can slowly go back to normal activities, but you will need to take steps to prevent another heart attack.
Symptoms
A heart attack is a medical emergency. If you have symptoms of a heart attack, call 911 or your local emergency number right away.
- DO NOT try to drive yourself to the hospital.
- DO NOT WAIT. You are at greatest risk for sudden death in the early hours of a heart attack.
Chest pain is the most common symptom of a heart attack.
- You may feel the pain in only one part of your body OR
- Pain may move from your chest to your arms, shoulder, neck, teeth, jaw, belly area, or back
The pain can be severe or mild. It can feel like:
- A tight band around the chest
- Bad indigestion
- Something heavy sitting on your chest
- Squeezing or heavy pressure
The pain most often lasts longer than 20 minutes. Rest and a medicine to relax the blood vessels (called nitroglycerin) may not completely relieve the pain of a heart attack. Symptoms may also go away and come back.
Other symptoms of a heart attack can include:
- Anxiety
- Cough
- Fainting
- Lightheadedness, dizziness
- Nausea and vomiting
- Palpitations (feeling like your heart is beating too fast or irregularly)
- Shortness of breath
- Sweating, which may be very heavy
Some people (including older adults, people with diabetes, and women) may have little or no chest pain. Or, they may have atypical symptoms such as shortness of breath, fatigue, and weakness. A "silent heart attack," which can also occur, is a heart attack with no symptoms.
Exams and Tests
Your health care provider will perform a physical exam and listen to your chest using a stethoscope.
- Your provider may hear abnormal sounds in your lungs (called crackles), a heart murmur, or other abnormal sounds.
- You may have a fast or uneven pulse.
- Your blood pressure may be normal, high, or low.
You will have an electrocardiogram (ECG) to look for heart damage. Often, certain changes on the ECG indicate you are having a heart attack, although a heart attack can also occur without ECG changes.
A blood test can show if you have heart tissue damage. This test can confirm that you are having a heart attack. The test is often repeated over time.
Coronary angiography may be done right away or later in the course of illness.
- This test uses a special dye and x-rays to see how blood flows through your heart.
- It can help your provider decide which treatments you need next.
Other tests to look at your heart that may be done while you are in the hospital:
- Echocardiography with or with stress testing
- Exercise stress test
- Nuclear stress test
- Heart CT scan or heart MRI
Treatment
IMMEDIATE TREATMENT
- You will be hooked up to a heart monitor, so the health care team can see how regularly your heart is beating.
- You will receive oxygen.
- An intravenous line (IV) will be placed into one of your veins. Medicines and fluids pass through this IV.
- You may get nitroglycerin and morphine to help reduce chest pain.
- You may receive aspirin, unless it would not be safe for you. In that case, you will be given another medicine that prevents blood clots.
- Dangerous abnormal heartbeats (arrhythmias) may be treated with medicine or electric shocks.
EMERGENCY PROCEDURES
Angioplasty is a procedure to open narrowed or blocked blood vessels that supply blood to the heart.
- Angioplasty is often the first choice of treatment. It should be done within 90 minutes after you get to the hospital, and usually no later than 12 hours after a heart attack.
- A stent is a small, metal mesh tube that opens up (expands) inside a coronary artery. A stent is usually placed right after or during angioplasty. It helps prevent the artery from closing up again.
You may be given drugs to break up the clot. This is called thrombolytic therapy. It is best if these drugs are given soon after the onset of symptoms, usually no later than 12 hours after it and ideally within 30 minutes of arriving at the hospital.
Some people may also have heart bypass surgery to open narrowed or blocked blood vessels that supply blood to the heart. This procedure is also called coronary artery bypass grafting or open heart surgery.
TREATMENT AFTER A HEART ATTACK
After several days, you will be discharged from the hospital.
You will likely need to take medicines, some for the rest of your life. Always talk to your provider before stopping or changing how you take any medicines. Stopping certain medicines can be deadly.
While under the care of your health care team, you will learn:
- How to take medicines to treat your heart problem and prevent more heart attacks
- How to eat a heart-healthy diet
- How to be active and exercise safely
- What to do when you have chest pain
- How to stop smoking
Strong emotions are common after a heart attack.
- You may feel sad
- You may feel anxious and worry about being careful about everything you do
All of these feelings are normal. They go away for most people after 2 or 3 weeks.
You may also feel tired when you leave the hospital to go home.
Most people who have had a heart attack take part in a cardiac rehabilitation program.
Support Groups
Many people benefit from taking part in support groups for people with heart disease.
Outlook (Prognosis)
After a heart attack, you have a higher chance of having another heart attack.
How well you do after a heart attack depends on several factors such as:
- The amount of damage to your heart muscle and heart valves
- Where that damage is located
- Your medical care after the heart attack
If your heart can no longer pump blood out to your body as well as it used to, you may develop heart failure. Abnormal heart rhythms can occur, and they can be life threatening.
Most people can slowly go back to normal activities after a heart attack. This includes sexual activity. Talk to your provider about how much activity is good for you.
References
Arnett DK, Blumenthal RS, Albert MA, et al. 2019 ACC/AHA guideline on the primary prevention of cardiovascular disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019;140(11):e596-e646. PMID: 30879355
Bohula EA, Morrow DA. ST-elevation myocardial infarction: management. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 38.
Giugliano RP, Braunwald E. Non-ST elevation acute coronary syndromes. In: Libby P, Bonow RO, Mann DL, Tomaselli, GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 39.
Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the evaluation and diagnosis of chest pain: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2021;144: ):e455. PMID: 34709879
Scirica BM, Libby P, Morrow DA. ST-elevation myocardial infarction: pathophysiology and clinical evolution. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 37.
Tamis-Holland JE, Jneid H, Reynolds HR, et al. Contemporary diagnosis and management of patients with myocardial infarction in the absence of obstructive coronary artery disease: a scientific statement from the American Heart Association. Circulation. 2019;139(18):e891-e908. PMID: 30913893
Version Info
Last reviewed on: 10/5/2022
Reviewed by: Thomas S. Metkus, MD, Assistant Professor of Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Internal review and update on 07/23/2023 by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
